Fair Square Medicare Wordmark

Does Medicare Cover Ketamine Infusion for Depression?

Dripping medication stock photo
By Ford Carlisle
Nov 23, 2022

Ways to Cover Your Ketamine Therapy Costs

If you or your loved ones

struggle with depression

and haven't found relief from traditional medications, you might consider ketamine infusion therapy. This alternative mental health therapy has proven effective for individuals with treatment-resistant depression.

Stay Up to Date on Medicare!

Join the Fair Square Medicare Newsletter to stay informed on cost savings, changes to Medicare, and other valuable healthcare information.
But what exactly is ketamine infusion, and will your insurance plan help cover the costs?
Keep reading to find out. In this article, we'll answer all your questions about ketamine infusion therapy and discuss ways to get coverage.

What Is Ketamine Infusion Therapy?

Ketamine infusion is an FDA-approved therapy for treatment-resistant depression.
It involves a 40-minute procedure — in a hospital or clinical setting — in which a doctor administers ketamine intravenously.
Ketamine infusion therapy requires multiple sessions:
  • It begins with an induction period — the patient typically receives six infusions over 2-3 weeks
  • Then follows the maintenance period — the dosage is slowly reduced to one infusion every 2-6 weeks

How Much Does Ketamine Infusion Therapy Cost?

A single ketamine infusion costs between $450 and $500.
The total cost of the Ketamine infusion therapy — which includes six ketamine infusions, a pretreatment consultation, and post-treatment follow-ups — is around $4,500.
Exact treatment costs may vary depending on your healthcare provider.

Does Medicare Cover Ketamine Infusions?

No.

Medicare

doesn't cover ketamine treatments for mental health conditions — like depression, anxiety, or mood disorders.
However, Medicare does cover a derivative of ketamine known as esketamine (Spravato). Spravato is an FDA-approved intranasal spray used on patients with treatment-resistant depression.
Note: To get Medicare coverage for Spravato,

you must be enrolled

in Medicare Part D or any Medicare Advantage Plan that covers prescription drugs. (Medicare Parts A and B don't cover Spravato).

Do Private Insurance Companies Cover Ketamine Infusions?

Typically, no.
Most private insurance companies only cover ketamine as an anesthetic. They probably won't cover ketamine treatments for depression.
However, insurance might cover certain parts of your treatment — like doctor visits or medical exams.
The extent of your insurance coverage depends on your plan and provider.

How Can I Cover the Costs of Ketamine Infusions?

Here are some ways to make ketamine infusions more affordable:
  • Talk to your insurance provider
  • Look for out-of-network reimbursements
  • Provide a Superbill
  • Use HSA/FSA accounts
  • Look into Advance Care
  • Seek Veteran Support
  • Ask about installment payments
Let's look at each option in more detail.

1. Talk to Your Insurance Provider

Check whether your insurance provider covers ketamine therapy. Some offer coverage under specific circumstances:
  • For example, if your provider classifies the treatment as “an infusion of a generic drug,” they may be able to cover some out-of-pocket expenses

2. Look for Out-of-Network Reimbursements

See if your insurance provider reimburses out-of-network claims. Pay your clinical provider for the service and ask your insurance for a reimbursement.
Most insurance companies accept out-of-network claims for healthcare services — unless their policy states otherwise. But each insurance company has different rules regarding out-of-network coverage. Talk to your provider for more info.

3. Provide a Superbill

A Superbill is an itemized list of all services provided to a client. It includes detailed visit summaries, doctors' names, CPT codes, etc.
Request a Superbill from your doctor. You might need it to claim your out-of-network coverage or get financial assistance with doctor visits, medical exams, etc.

4. Use HSA/FSA Accounts

HSA (Healthcare Spending Account) and FSA (Flexible Spending Account) are pre-tax accounts that help you save money for qualified healthcare expenses. 
Paying for your ketamine therapy using these "pre-tax" dollars is like receiving a discount on your treatment.
Note: Stop HSA contributions at least six months before enrolling in Medicare to avoid potential tax penalties.

5. Look Into Advance Care

Advance Care

provides patients with affordable medical financing options. The Advance Care Card offers interest-free financing, affordable monthly payments, and flexible terms.
Using Advance Care can help reduce up-front expenses.

6. Seek Veteran Support

The Ketamine Fund

offers free ketamine therapy to veterans suffering from PTSD, anxiety, depression, and other treatment-resistant disorders.

7. Ask About Installment Payments

Ask your healthcare provider if they provide installment payment options. Enrolling in a payment plan can help you cover up-front treatment costs.

Will Ketamine Infusion Coverage Change in the Future?

It's possible! Insurance companies might decide to cover ketamine infusion therapy as more research shows its safety and effectiveness in treating depression. 
Several organizations are already trying to spark this change:
For example, a non-profit organization called the

Ketamine Task Force

works to make ketamine infusion therapy more accessible. Their goal is to get insurance providers to approve coverage for ketamine infusions and provide fair reimbursement rates to ketamine providers.

Takeaway

Ketamine infusion therapy is an effective depression treatment — with results lasting days or weeks. Talk with your doctor before starting or stopping treatment for depression. This content is for informational purposes only.
Currently, Medicare doesn't provide coverage of ketamine treatments for depression. But you can seek out-of-network reimbursements, HSA/FSA accounts, and other payment options to reduce your expenses.
If you need help, our team at

Fair Square Medicare

has your back. Our advisors can answer any questions you have about Medicare coverage.
Give us a call at 1-888-376-2028.

Stay Up to Date on Medicare!

Join the Fair Square Medicare Newsletter to stay informed on cost savings, changes to Medicare, and other valuable healthcare information.

Recommended Articles

Medicare Enrollment Periods stock image
Explaining the Different Enrollment Periods for Medicare
Feb 3, 2023
Cover image
Does Medicare Cover RSV Vaccines?
Sep 13, 2023
Cover image
Fair Square Client Newsletter: AEP Edition
Oct 2, 2023
Pile of junk in a house, hoarder room pile of household equipment needs clearing out stock photo
Does Medicare Cover Hoarding Cleanup?
Jan 10, 2023
amazon box
What If I Don't Like My Plan?
Jun 8, 2020
Older woman during an eye exam
Does Medicare Cover Diabetic Eye Exams?
Jan 11, 2023
Emergency section of a hospital exterior stock photo
How Does Medicare Pay for Emergency Room Visits?
Nov 21, 2022
Philadelphia skyline at sunset stock image
13 Best Ways for Seniors to Stay Active in Philadelphia
Mar 7, 2023
COVID-19 at home test stock image
Does Medicare Cover COVID Tests?
Dec 21, 2022
An elderly couple discusses their healthcare and insurance needs with another woman stock image
Medicare Guaranteed Issue Rights by State
Feb 10, 2023
Fair Square
Is Displacement Affecting Your Medicare Coverage?
Oct 6, 2022
Cover image
Can Medicare Advantage Plans be Used Out of State?
Jun 12, 2023
Enroll in Social Security step-by-step with the help of Fair Square stock image
How to Enroll in Social Security
Apr 28, 2023
Medigap plan letters on outstretched fingers stock image
How Do Medigap Premiums Vary?
Apr 12, 2023
Close up of a senior clutching their right wrist in pain stock photo
Does Medicare Cover Cala Trio?
Nov 23, 2022
Medicare check yes stock image
How to Apply for Medicare?
Jul 15, 2022
cartoon hospital and male doctor stock image
Can I Have Two Primary Care Physicians?
Oct 3, 2022
Cover image
How Can I Get a Replacement Medicare Card?
Aug 14, 2023

More of our articles

13 Best Ways for Seniors to Stay Active in Jacksonville

14 Best Ways for Seniors to Stay Active in Seattle

14 Best Ways to Stay Active in Charlotte

2024 Cost of Living Adjustment

2024 Fair Square NPS Report

Are Medicare Advantage Plans Bad?

Can Doctors Choose Not to Accept Medicare?

Can I Change My Primary Care Provider with an Advantage Plan?

Can I Use Medicare Part D at Any Pharmacy?

Do All Hospitals Accept Medicare Advantage Plans?

Does Medicare Cover Abortion Services?

Does Medicare Cover Air Purifiers?

Does Medicare Cover an FMT?

Does Medicare Cover Bladder Sling Surgery?

Does Medicare Cover Boniva?

Does Medicare Cover Cervical Disc Replacement?

Does Medicare Cover Driving Evaluations?

Does Medicare Cover Flu Shots?

Does Medicare Cover Geri Chairs?

Does Medicare Cover Hearing Aids?

Does Medicare Cover Home Heart Monitors?

Does Medicare Cover Hypnotherapy?

Does Medicare Cover Incontinence Supplies?

Does Medicare Cover Inspire for Sleep Apnea?

Does Medicare Cover Jakafi?

Does Medicare Cover Kidney Stone Removal?

Does Medicare Cover Krystexxa?

Does Medicare Cover Kyphoplasty?

Does Medicare Cover Mental Health?

Does Medicare Cover Mouth Guards for Sleep Apnea?

Does Medicare Cover Nexavar?

Does Medicare Cover Ozempic?

Does Medicare Cover Penile Implant Surgery?

Does Medicare Cover Piqray?

Does Medicare Cover Service Animals?

Does Medicare Cover TENS Units?

Does Medicare Cover the WATCHMAN Procedure?

Does Medicare Cover Tymlos?

Does Medicare Cover Vitamins?

Does Medicare Cover Wart Removal?

Does Medicare Pay for Bunion Surgery?

Does Medicare Pay for Varicose Vein Treatment?

Does Your Medicare Plan Cover B12 Shots?

Finding the Best Dental Plans for Seniors

How Are Medicare Star Ratings Determined?

How Do Medicare Agents Get Paid?

How Does Medicare Cover Colonoscopies?

How Does the End of the COVID-19 Public Health Emergency Affect Your Medicare?

How Medicare Costs Can Pile Up

How Much Does Medicare Part B Cost in 2025?

How Much Does Open Heart Surgery Cost with Medicare?

How Much Does Rexulti Cost with Medicare?

How Much Does Trelegy Cost with Medicare?

How Much Does Xeljanz Cost with Medicare?

How to Become a Medicare Agent

How to Deduct Medicare Expenses from Your Taxes

How Your Employer Insurance and Medicare Work Together

Is Botox Covered by Medicare?

Is PAE Covered by Medicare?

Is the Shingles Vaccine Covered by Medicare?

Medicare Advantage MSA Plans

Medicare Explained

Medicare Savings Programs in Kansas

Medigap vs. Medicare Advantage

The Easiest Call You'll Ever Make

Top 10 Physical Therapy Clinics in San Diego

What is a Medicare Beneficiary Ombudsman?

What People Don't Realize About Medicare

What You Need to Know About Creditable Coverage

When to Choose Medicare Advantage over Medicare Supplement

Why Is Medicare So Confusing?

Why You Should Keep Your Medigap Plan

Your Medicare One-Stop-Shop

Your guide to Medicare Parts A & B, Medicare Advantage, and Medigap. 100% free.
Get the Fair Square Bulletin

Medicare savings tips, helpful guides, and more.

About

Medicare 101

Current Clients

Medicare Supplement Plans

Medicare Advantage Plans

Fair Square 2025

Terms of Use
Notice of Privacy Practices

Virgil Insurance Agency, LLC (DBA Fair Square Medicare) and www.fairsquaremedicare.com are privately owned and operated by Help Button Inc. Medicare supplement insurance plans are not connected with or endorsed by the U.S. government or the federal Medicare program. This is a solicitation of insurance. A licensed agent/producer may contact you. Medicare Supplement insurance is available to those age 65 and older enrolled in Medicare Parts A and B and, in some states, to those under age 65 eligible for Medicare due to disability or End-Stage Renal disease. Virgil Insurance Agency is a licensed and certified representative of Medicare Advantage HMO, HMO SNP, PPO, PPO SNP and PFFS organizations and stand-alone PDP prescription drug plans. Each of the organizations we represent has a Medicare contract. Enrollment in any plan depends on contract renewal. The plans we represent do not discriminate on the basis of race, color, national origin, age, disability, or sex. Plan availability varies by region and state. For a complete list of available plans please contact 1-800-MEDICARE (TTY users should call 1-877-486-2048), 24 hours a day/7 days a week or consult www.medicare.gov. © 2025 Help Button Inc

We do not offer every plan available in your area. Any information we provide is limited to those plans we do offer in your area. Please contact Medicare.gov or 1-800-MEDICARE to get information on all of your options.

MULTIPLAN_FairSquareMedicare_01062022_M